Wise Registry Cleaner is a free registry cleaner for Windows with many advanced features.
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Do NOT use Registry Cleaners
Among other things, registry backups are created automatically, registry defragmentation is possible, and software updates are performed in place.
I've used Wise Registry Cleaner many times over the years, and there's still not much to complain about.
WiseCleaner.com releases some great software, like a file finder, a program uninstaller, and this registry cleaner.
